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Avoid blood-thinning supplements like fish oil, ginger, turmeric, or high-dose vitamin E for 48 hours before injection
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2 Search strategy and inclusion criteria This mini-review was based on a targeted literature search conducted in PubMed/MEDLINE and Scopus from January 2015 to August 2025, using the keywords GLP-1 receptor agonists, exercise, physical activity, obesity, type 2 diabetes, and weight loss. Additional terms ( lean mass, body composition, insulin sensitivity, cardiometabolic, combined intervention ) were used in secondary searches
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Based on data from the phase 2 clinical trial of retatrutide (NCT04881760), published in the New England Journal of Medicine in 2023, gastrointestinal adverse events were among the most frequently reported side effects across all dose groups
