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More importantly, the weight loss caused by tirzepatide in these animals likely contributed to adverse outcomes independently of the drug itself

Las causas del aumento de peso son muy complejas, y debemos asegurarnos de abordar tambin esos aspectos, aade

cardiovascular disease [51], and atherosclerotic plaques [52]

The two groups successfully maintained a 12-kg weight loss during 1 year although the GLP-1RA group was slightly more successful

Furthermore, 5-HT neurons in the DRN (5-HT DRN ) projecting to the ventral tegmental area (VTA) inhibit hedonic feeding via 5-HT 2C receptor and reduced potassium channel currents [51]
