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Who Benefits Most From This Combination Therapy Patients with type 2 diabetes and a body mass index (BMI) above 27 kg/m are ideal candidates for metformin-semaglutide combination therapy, especially if monotherapy with metformin has not achieved target A1c levels

While this eliminates injections, it demands strict timing to take on an empty stomach with minimal water, then wait at least 30 minutes before eating or taking other medications

Patients with pre-existing gastrointestinal conditions may experience different tolerability and should discuss their medical history with their healthcare provider

PYP scan evaluating for TTR amyloid was negative and laboratory workup did not suggest AL amyloid, Fabrys, Hemochromatosis, or storage disease

Still, first, you need to recognize that you might have no symptoms or minor symptoms such as gastrointestinal bloating or mild constipation