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Description
health insurance landscape creates both the opportunity and the constraint: commercial insurance covering GLP-1 for diabetes generates large, well-reimbursed prescription volumes, but coverage for obesity indications varies widely, with Medicare explicitly prohibited from covering weight loss drugs until the Treat and Reduce Obesity Act passes a legislative gap that excludes tens of millions of Medicare beneficiaries from covered GLP-1 obesity access

there is also data to suggest that slower titration regimens (employed in GLP-1-insulin combo therapies), may reduce rates of nausea and vomiting further

7 Department of Medicinal Chemistry, Faculty of Pharmacy, University of Tabuk, Tabuk, 71491, Saudi Arabia

In 2005, the first GLP-1 agonist, exenatide, was approved for the management of Type 2 diabetes mellitus (T2DM) [6]
In a prospective open-label pilot study by Krajnc et al., patients had chronic IIH under treatment (some had persistent papilledema ~ 70% at baseline) [27]
