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Men with diabetes experience erectile dysfunction at rates of 50-75%, driven by vascular damage, neuropathy, and hormonal changes that tirzepatide's metabolic benefits might address

Patients with a history of severe gastrointestinal disease, particularly those with inflammatory bowel disease, severe gastroesophageal reflux disease, or history of pancreatitis, require careful evaluation before considering this therapy

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Furthermore, systematic reporting enhances drug safety surveillance, strengthens pharmacovigilance, and informs regulatory decisions Acknowledgments Dr Yovan Sumaruth, Dr Faris Chater, and Dr Rudramun Gopal all contributed equally to the work and should be considered co-first authors

At the same time, the desire to breastfeed is equally valid