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During this ramp-up period, your brain's satiety centers become increasingly responsive to the GLP-1 signal, meaning you'll naturally eat smaller portions without intense hunger

You start low, assess tolerance, and increase gradually

By providing the right information and support, teaching them to monitor their heart rate, and empowering them to take an active role in their health, patients can manage this side effect effectively

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Patients with certain variants may plateau earlier or require combination therapy sooner for optimal results