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It reduces appetite by acting on hunger centres in the brain, slows stomach emptying so you feel full longer, improves insulin secretion, reduces glucagon production, and helps target visceral (belly) fat

Umpierrez, G., Tof Povedano, S., Prez Manghi, F., Shurzinske, L

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Gastrointestinal tolerability and weight reduction associated with tirzepatide in adults with obesity or overweight with and without type 2 diabetes in the SURMOUNT-1 to -4 trials