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This is one reason telehealth platforms began offering compounded semaglutide and tirzepatide at lower costs than name-brand medications

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Houschyar et al

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Short Half-Life Native GLP-1 has a very short half-life (12 minutes) due to rapid degradation by dipeptidyl peptidase-4 (DPP-4) enzyme

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Additionally, injecting into areas with potentially reduced absorption, or failing to rotate injection sites may result in inconsistent drug delivery

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