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Both studies showed that there was a significant increase in retained gastric content in patients who were using GLP-1-RA which can lead to aspiration during a surgical procedure

injections of 100 nmol kg 1 MK-801, 100 nmol kg 1 GLP-1, 100 nmol kg 1 GLP-1MK-801 or vehicle (isotonic saline)

At least 70% are on GLP1 medications

doi: 10.1056/NEJMoa1509225 48 BolliGBMunteanuMDotsenkoSNiemoellerEBokaGWuYet al

This doesn't just affect the stomach - it changes how the entire gastrointestinal tract works by suppressing normal digestive patterns
