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Together with other aspects of the PWS phenotype including, in many cases, a reduced sensitivity to pain, hyperphagia results in life-threatening obesity and life-shortening complications for some people with PWS

It is unclear how long treatment must continue to maintain weight loss, and whether chronic therapy is needed (as in adults)especially since drug cessation leads to rapid weight regain (35)

Januvia can be prescribed by itself or with other diabetes medicines

Suicide in young people: screening, risk assessment, and intervention

GLP-1 receptor activation appears to release the accelerator (reducing inflammatory effector cells) while strengthening the brake (enhancing regulatory cells)