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SURMOUNT-1 results (72 weeks, adults with obesity): 5 mg dose: approximately 15% body weight loss 10 mg dose: 19.5% body weight loss 15 mg dose: 22.5% body weight loss Placebo: 3.1% body weight loss At the 15 mg maximum dose, the average participant lost about 52 pounds over 72 weeks
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In human microvascular endothelial cells as well as human umbilical vein endothelial cells, Eltzschig and colleagues showed that hypoxia increased DPP4 mRNA and protein level (175), whereas another study by Shigeta et al
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