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PlexusDx Precision Peptide Genetic Test analyzes variants like GLP1R rs6923761 and GIPR rs1800437 that correlate with semaglutide response speed and intensity

At week 52, the total daily insulin dose was decreased from baseline with oral semaglutide 14 mg for patients on basal, premixed and basal-bolus insulin, and were generally consistent regardless of background insulin regimen (see Fig

The American Diabetes Association similarly recommends at least 150 minutes of moderate-intensity exercise weekly, spread over at least 3 days, with no more than 2 consecutive days without activity

The Need for Future Research Given the separate benefits of semaglutide and estradiol, there is a clear need for more research into their combined effects

TABLE 1 Demographic charactristics of participants