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PubMed Central , "People Taking GLP-1 Weight Loss Drugs like Ozempic Started Moving Less." ScienceDaily , Accessed 17 June 2026

But another symptom many users report is fatigue

Risk of developing retinopathy in Diabetes Control and Complications Trial type 1 diabetic patients with good or poor metabolic control

In addition to the medications known side effects, potential risks include disordered eating and mental health impacts

Thus, in order to have GLP/GIP analogs with lasting effects, alterations of the peptides needed to be made in order to prevent their rapid metabolism by DPP-4 and oral administration could not be used
