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Further, studies of transgenic animals controlling the expression of green fluorescent protein (GFP) downstream of the GLP-1R promoter found GLP-1R promoter activity in pancreatic - and -cells, vascular smooth muscle, cardiac atrium, the gastric antrum and pylorus, enteric neurons, and vagal and dorsal root ganglia [395]
GLP-1 RAs reduce adipose tissue mass in subcutaneous and visceral depots and increase circulating adiponectin levels

( / mice on a high-fat, high-cholesterol diet

The remaining fat becomes more resistant to mobilization

Personalized GLP-1 Therapy with PlexusDx Genetic Insights Not everyone responds the same way to GLP-1 medications
