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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Yun S.P., Kam T.I., Panicker N., Kim S., Oh Y., Park J.S., Kwon S.H., Park Y.J., Karuppagounder S.S., Park H., et al

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5 Liraglutide is injected once daily, while albiglutide, dulaglutide, and semaglutide are injected once weekly

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Lys 16 Replacing the Gly 22 of GLP-1 with Ala or Aib slightly decreased both its affinity and activity (Ala IC 50 : 0.27 nM0.57 nM;EC 50 : 2.6 nM4 nM)