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Routine calcitonin screening in the general population has poor positive predictive value , as calcitonin elevations occur in numerous benign conditions including C-cell hyperplasia, chronic kidney disease, proton pump inhibitor use, and thyroiditis
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Approval can only follow evidence, and that evidence is just now emerging, says Vidmar
doi: 10.1016/S2213-8587(21)00246-1 21 EdqvistJRawshaniAAdielsMBjorckLLindMSvenssonAMet al
Importantly, the FDA has identified and communicated other potential cancer concerns with this drug class
