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In rodent studies, semaglutide attenuated exercise-induced myocardial injury by suppressing inflammation and oxidative stress [159], whereas dulaglutide reduced the levels of proinflammatory cytokines (e.g., IL-1, IL-6, and MCP-1) in human fibroblast-like synoviocytes via inhibition of c-Jun N-terminal kinase/NF-B signalling [160]

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0.5% methylcellulose) was administered by oral gavage to overnight-fasted mice 1 h prior to re-feeding
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