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Nevertheless, it is essential that patients and healthcare professionals (HCPs) are aware of the right procedures to follow to prevent GI AEs from arising or, if they occur, to mitigate their effects and improve adherence and persistence to the treatment

Analysis of tissue samples found that GLP-1 receptor proteins were most numerous in the pancreas, consistent with the drugs' known benefits in diabetes, but the heart had the second-highest concentration

Patients taking concurrent metformin, which independently causes diarrhea in 10 to 20% of users, should be especially vigilant about fluid replacement