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Data analysed by one-way ANOVA, multiple comparison, Bonferroni post hoc test ( c , e , g , l , n , p , v , x and z ) and two-way repeated measures ANOVA to assess main effects of treatment ( i , j , q , s and t )

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Akkermansia muciniphila and microbial strains that produce butyrate such as Clostridium butyricum can augment GLP-1 production through natural stimulation of the L-cells