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For practical meal planning guidance while on these medications, explore the tirzepatide meal plan , the semaglutide diet plan , and our comprehensive guide on what to eat on tirzepatide

5 Figure 1: Effect of once-weekly tirzepatide, compared with semaglutide, on lipid profile 5 GLP-1s are also being investigated for the prevention and treatment of heart failure

Overall, treatment with semaglutide was associated with a reduction in the studys composite outcomecardiovascular death, nonfatal myocardial infarction or nonfatal strokeof 20% compared to a placebo, and it was linked to a safe and well-tolerated profile. SELECT trial results were published in the New England Journal of Medicine in November

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