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Most clinicians use 1.21.6 g/kg of adjusted body weight daily during active weight loss, recognizing that GLP-1-induced satiety can suppress protein-rich food consumption

As the authors stated, To our knowledge this is the first lifestyle intervention study where remission of T2D has been studied with 100% remission with a feeding study using meals and food obtained from local grocery stores. However, unlike GLP-1 drugs, a calorie-restricted diet with the same macronutrient composition as the Zone diet causes weight loss without loss of lean body mass in both individuals with type 2 diabetes (7) as well as those with pre-diabetes (8)

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Gastroenterology 123 , 11201128 (2002)

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