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[18] [1] These gastrointestinal effects could potentially influence taste perception, though the exact mechanism is not established
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A new paradigm for treating to target with second-generation obesity medications

Various hydrogel formulations, differentiated by their physicochemical properties and release kinetics, are summarized in Table 1D

The core machinery of this axis is the IP3R-GRP75-VDAC1 tripartite complex, where GRP75 (Szabadkai et al., 2006) acts as a linker protein that physically bridges the IP3R on the ER (Bartok et al., 2019) to the VDAC1 channel on the mitochondria (Rapizzi et al., 2002), funneling ions directly into the mitochondrial matrix (Szabadkai et al., 2006)
