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Wegovy, in particular, is FDA-approved for weight loss in adults with obesity or overweight, and has shown consistent, proven results in clinical studies, with patients achieving significant weight reduction when combined with a reduced-calorie diet and increased physical activity

The authors showed that a 12-week treatment with exenatide was associated with a significant reduction in liver enzymes compared to treatment with metformin

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Protective effects during pressure overloadinduced cardiac hypertrophy have also been reported for semaglutide in rats that underwent transverse aortic constriction

A 2025 review in Otology & Neurotology of FDA adverse-event reports looked at how often this happens
