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A small clinical trial confirmed these findings, showing that exenatide, another GLP-1 agonist, significantly reduced intracranial pressure in patients with idiopathic intracranial hypertension, greatly improving headache symptoms

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Peterli et al., 2012), which may be due to an increase in the number of L cells or in their secretion, or may reflect the flow of nutrients to more densely populated areas of L cells in the distal small intestine

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