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Theoretical considerations: Some researchers have raised theoretical concerns about GLP-1 effects on reproductive hormones, but clinical evidence of harm is lacking
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These are legitimate concerns
In the STEP clinical trials, patients weighing over 100 kg (220 lbs) tended to need the full 2.4 mg maintenance dose for optimal results, while those under 80 kg (176 lbs) sometimes achieved their goals at 1.0 or 1.7 mg
Direct identification of ligand-receptor interactions on living cells and tissues
