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Previous studies suggest that agonism of the cannabinoid receptors, by either endocannabinoids or exogenous cannabinoids, acutely stimulates food craving, intake, and reward, and promotes the storage of energy in adipose tissues, whereas antagonism of the cannabinoid receptors reduces food intake and body weight 1519

Exendin-4 attenuates atherosclerosis progression via controlling hematopoietic stem/progenitor cell proliferation

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P., Kaneko, S., Lee, C

However, the synergistic effects of GLP-1RA-based therapies with traditional pain medications (such as gabapentinoids or opioids) could be explored in future trials to better assess their role in comprehensive neuropathic pain treatment regimens