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6.6 Incretin Receptor Activation Reduces the Chronic Inflammation Response GLP-1 receptor agonists have shown clear anti-inflammatory effects [116, 166]

Global, regional, and national burden of type 2 diabetes mellitus caused by high BMI from 1990 to 2021, and forecasts to 2045: analysis from the global burden of disease study 2021.Frontiers in public health, 2.Trinh D, McDonald M Formulary Management of Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists: Environmental Scan [Internet].Ottawa (ON): Canadian Agency for Drugs and Technologies in Health

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Understanding why these FDA-approved GLP-1 receptor agonists may not work as expected requires examining multiple factorsfrom medication dosing and administration technique to underlying medical conditions and lifestyle behaviors

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