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Medical Dialogues / DCGI Approval Notice CDSCO Approved BMI Thresholds DCGI has approved semaglutide for obesity in adults with BMI 30 kg/m, or BMI 27 kg/m with at least one weight-related comorbidity (hypertension, T2D, dyslipidaemia, or sleep apnea)

More serious complications such as pancreatitis or gallbladder issues are considered uncommon but may still require medical monitoring

Trouble with insurance coverage is a key reason Dushay said shes seen patients switch to the Wegovy pill

Lipolytic rate-limiting enzymes include hormone-sensitive lipase (HSL) and lipoprotein lipase (LPL), which are affected mostly by medullary hormones such as adrenal and norepinephrine, and glucose-metabolism-related hormones such as insulin and glucagon

Importantly, these medications are not generally recommended in patients with severe gastrointestinal disease, including severe gastroparesis, which may be relevant when considering their use in individuals with Crohn's disease