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These results also align with previous retrospective research showing enhanced renal protection when combining GLP-1RA with SGLT2i compared to SGLT2i alone in T2D patients, including lower risks of MAKE (HR, 0.73

Figure 1 Promotion of Bone Formation and Possible Mechanisms GLP-1 Promotes Bone Formation Glucagon-like peptide-1 increases the number of osteoblasts
Mathiesen DS, Lund A, Vilsbll T, Knop FK, Bagger JI
This means that new safety findings are continuously collected and evaluated

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