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Tirzepatide (Zepbound, Mounjaro) A 2022 clinical trial of people with obesity or overweight found that a once-weekly tirzepatide injection produced an average weight loss of 15%21% in 72 weeks (a bit less than a year and a half)

Where $V$ is the required solvent volume (mL), $m$ is the total peptide mass in the vial (mg), and $C$ is the targeted protocol concentration (mg/mL)

However, no prior studies have evaluated its economic value for obesity treatment in nondiabetic populations after the approval of tirzepatide

95 GLP-1RAs can also influence bile acid composition through FXR and TGR5, as described by Gether et al

Patients notice more energy, better fasting glucose levels, and smaller waist measurements