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Description
For a drug to passively diffuse through this layer, it typically needs to be: Small in molecular size Lipophilic (fat-soluble) However, GLP-1 molecules: Are too large and hydrophilic Cannot naturally penetrate the skin barrier Even if GLP-1 patches claim to have GLP-1 drugs, the molecules cannot pass through the skin barrier without support

Next-generation pain-free injection Nano Microneedle Patch

10.1152/ajprenal.00394.2015 18

In trials and real-world experience, people have used GLP-1 medications safely for many years

[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Munigala S., Gelrud A., Agarwal B
