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Description
Glp1r expression is undetectable by quantitative PCR in peritoneal or adipose tissue macrophages (37), although Lyz2 -Credriven deletion of Glp1r ( Glp1r Lyz2/ ) abolishes expression in bone marrowderived macrophages (38)
The medication comes as a once-weekly subcutaneous injection
The approval addresses the growing need for treatments in the face of increasing obesity rates in the U.S
On the other hand, injections can create psychological resistance
Patients must be screened for liver or kidney impairment as both increase the risk of lactic acidosis in patients on this medication
