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Endotoxemia Lipopolysaccharide (LPS) is a major component of the outer membrane of all gram-negative bacteria that can trigger the synthesis and release of pro-inflammatory cytokines such as TNF, interleukin 1 (IL-1), and inducible nitric oxide synthase (iNOS) (Zhang et al., 2000

J Immunol 172:442448

Negatively charged nanoparticles have superior tolerability in comparison to their positively charged particles [135]

This work was also funded by the German Research Foundation (DFG) with the Collaborative Research Center CRC 1316 Transient atmospheric plasmas: from plasmas to liquids to solids (projects A5 and A7) at Ruhr University Bochum