companies that make glp 1 drugs Shortages improve for Lilly's GLP-1 weight loss drugs, bumping sales forecast by $3bn The Biggest Winner of GLP-1

Abbreviations CKD: Chronic kidney disease CVOT: Cardiovascular outcome trial DKD: Diabetic kidney disease ESKD: End-stage kidney disease GLP-1RA: Glucagon-like peptide-1 receptor agonist(s) ITT: Intention-to-treat MMRM: Mixed model for repeated measures PSM: Propensity score matching RAS: Reninangiotensin system SGLT2: Sodiumglucose cotransporter 2 SGLT2i: SGLT2 inhibitor(s) SMD: Standardised mean difference UACR: Urinary albumin/creatinine ratio References Thomas MC, Brownlee M, Susztak K et al (2015) Diabetic kidney disease

These conditions require immediate medical intervention to prevent further complications

These tablets are a therapeutic equivalent generic version of KOMBIGLYZE XR (saxagliptin and metformin hydrochloride extended release) tablets that have been approved by the U.S

SGLT2i versus DPP4i initiation was associated with a 14% lower dementia risk in the intention-to-treat analysis (HR 0.86, 95% CI 0.790.94

Unfortunately, only 56% of people with T2D had optimal risk factor control [4, 5]