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Description
The primary goal for persons with diabetes is to manage their blood glucose

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Summary: Retatrutide commonly causes bowel changes including diarrhoea, constipation, and abdominal discomfort due to its activation of GLP-1 receptors throughout the gastrointestinal tract, which alters gut motility

Receptor binding at GLP-1R activates adenylyl cyclase via Gs, raising intracellular cAMP and recruiting both protein kinase A and Epac2 effectors

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