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1416 Beyond compositional shifts, the functional consequences of dysbiosis are particularly relevant: the microbiota contributes to obesity pathophysiology by driving the production of short-chain fatty acids (SCFAs), modulating bile acid metabolism, and influencing immune and inflammatory pathways

For regulatory updates, see Retatrutide News and FDA Approval Timeline

Ethics declarations Conflict of interest AFB, VBS, FGDF and STF have no conflicts of interest that are directly relevant to the content of this article

Kidney function tests check creatinine levels and calculate the estimated glomerular filtration rate (eGFR)
Our results suggest that thyroid cancer risk should be considered with GLP-1 receptor agonists, particularly in patients treated for 1 to 3 years, Jean-Luc Faillie, MD, PhD , professor and head of the department of medical pharmacology and toxicology at Montpellier University Hospital and University of Montpellier in France, and colleagues wrote