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Methodology For the preparation of this review, we carried out a literature search using SciFinder , PubMed, and Scopus

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This metabolic penalty persists for years and makes maintaining weight loss without pharmacological support extraordinarily difficult

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The two pharmaceutical leaders in this space Novo Nordisk and Eli Lilly have seen astonishing growth in sales of their GLP-1 drugs for diabetes and obesity and have struggled to keep up with demand even at premium prices

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Tirzepatide carries a boxed warning regarding thyroid C-cell tumors observed in rodent studies, and is contraindicated in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

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If you still have remaining doses of your old medication, do not take them and dispose of them in your medical sharps container

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