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This is not typical of incretin-based therapies and appears to be unique to retatrutide, possibly related to the glucagon receptor component

They include semaglutide (found in Ozempic, Wegovy, and Rybelsus), tirzepatide (found in Mounjaro and Zepbound), and liraglutide (found in Victoza and Saxenda)

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When these medicines stimulate GLP-1 receptors in the stomach, they also slow gastric emptying, or how quickly food moves from your stomach to the lower intestine

Prevention: the most powerful before and after Perhaps the most underappreciated result from the SURMOUNT program is the diabetes prevention data