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A Nature Medicine analysis of the structural and pharmacological data provided mechanistic context for these outcomes, linking the superior efficacy to the additive contributions of all three receptor pathways [9]

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for example, an analysis of realworld data from the UK showed that liraglutide reduced HbA 1c to a greater extent than lixisenatide (mean treatment difference [95% confidence interval (CI)] 0.3%point [0.56
