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Description
Ablation of these neurons in mice reduces active GLP-1 by 60% in the brainstem and almost 80% in the hypothalamus and spinal cord [13,21,23]

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Similar to when administered by IV, GLP-1 QMP showed a 2.1-fold extended plasma half-life compared to GLP-1 WT (Supplementary Table 4)
10.1534/g3.118.200300 74 PrasadA.PorterD

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