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The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and abdominal pain

Function The GLP-1 receptor (GLP-1R) is a seven-segmented transmembrane protein with an extracellular amino terminus and an intracellular carboxyl terminus

Elevated blood levels of GLP1 following a meal may depend upon mechanical forces such as gastric distension (Mller et al., 2019

Early studies suggest that modulation of the gut-thyroid axis through GLP-1RAs represents a plausible mechanism linking metabolic therapies to improved autoimmune outcomes, though dedicated studies in AITD are needed [45,46]