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Where public coverage is limited and self-pay remains the main route, adoption follows a clear S-curve tied to the affordability ratio (AR) the share of a consumers disposable income required for one month of therapy
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For context, in one study of 175 people with overweight or obesity, participants taking semaglutide: Lost an average of 15 pounds (about 6% of their body weight) within three months Lost an average of 27 pounds (about 11% of their body weight) after six months Recommended lifestyle changes during GLP-1 therapy GLP-1 medications can boost weight loss by increasing satiety and reducing food cravings