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In the clinical studies so far, participants have generally needed to meet these requirements: BMI of 30 or above (classified as obese), or BMI of 27 or above with weight-related health conditions like type 2 diabetes, high blood pressure or dyslipidemia Adults aged 18 and over No history of certain medical conditions like pancreatitis or severe kidney disease Not pregnant or breastfeeding What is the dosing schedule of retratrutide, and how is it administered