is glp-1 the same as zepbound Compare Options | Ozempic v Mounjaro | WeightWatchers What to know about how

J Endocrinol Metab 11(5):95107 Liu Y et al (2023) The weight-loss effect of GLP-1RAs glucagon-like peptide-1 receptor agonists in non-diabetic individuals with overweight or obesity: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.He L, Wang J, Ping F, Yang N, Huang J, Li Y

Ex9-39 was measured using antibody 3145 raised in rabbits immunized with exendin-4, which shows 100% cross-reactivity with Ex9-39 but only 0.01% cross-reactivity with GLP-1, glucagon, and GIP (69)

Tirzepatide is a newer dual GLP-1/GIP agonist that targets two receptors simultaneously, and clinical data has demonstrated even greater average weight loss compared to single-receptor medications

[1] [2] The medication works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in response to elevated blood glucose levels, suppresses glucagon release, and slows gastric emptying