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Introduction Parkinsons disease (PD) is one of the most disabling diseases globally (1)

Overall, the findings from these two recently completed cardiovascular outcomes trials suggest that the increases in HR associated with the short-acting GLP-1 RA, lixisenatide, or the long-acting GLP-1 RA, liraglutide, do not lead to an increased risk of major adverse cardiac events in patients with T2DM and high cardiovascular risk

From this process, 107 papers were excluded, and 262 papers were sought for retrieval for full text

When they first came to market for diabetes, they noticed a side effect was weight loss. A potentially complex treatment option The patient side of the equation can be complex, as some experts believe these medications, whether for diabetes or weight loss, may need to be taken throughout a persons life, as a direct treatment or maintenance therapy

Most weight loss occurs within the first 68 to 72 weeks of treatment, but some people notice appetite changes within a few weeks