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On the other hand, the decreasing pattern of the hormone levels observed in both MO and PLC groups seems unrelated to dietary changes since no differences have been noted in nutrient intakes during the intervention in any of the groups (Table S4)

This can lead to kidney failure and premature death if dialysis or a kidney transplant are unavailable

Extrapolating from animal studies should also be done cautiously, as species-specific differences in microbiota composition, metabolism, and drug pharmacokinetics can markedly affect translational relevance

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