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In the landmark SCALE Obesity and Prediabetes trial, published in the New England Journal of Medicine, 3,731 patients without type 2 diabetes were randomized to receive either liraglutide 3.0mg or placebo daily for 56 weeks

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Some researchers use an uneven split where the larger dose comes at the beginning of the week

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Tirzepatide was titrated up to a maximum dose of 10 mg or 15 mg

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