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BMJ Open Diabetes Res Care 2021;9(1)

These non-hormonal medications help reduce abdominal obesity, improve insulin sensitivity, and lower inflammatory signaling

Excess weight promotes the development of a wide range of pathologies (insulin resistance, hypertension, chronic inflammation, dyslipidemia), which increase the risk of complications such as type 2 diabetes, cardiovascular disease, hepatic steatosis, several types of cancer and reduce life expectancy

While tirzepatide is not approved as a treatment for hypertension, many patients with obesity-related high blood pressure experience improvements during treatment

It helps reduce blood cholesterol, inflammation, and blood pressure, supporting overall heart function