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Tesamorelin sits apart from the incretin class entirely, working via growth hormone release and currently lacking large non-HIV obesity trials published 20242026 [12][13]
Obesity involves persistent changes to metabolic set points, hunger hormones, and energy regulation that do not reset after weight loss
Even the maximum 15mg dose requires only 37.5 units, which is barely a third of a full 1 ml syringe
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