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While human BAT was previously thought to be detectable only in infants and Arctic indigenous peoples, functional imaging studies have demonstrated the presence of BAT depots in adult humans at multiple sites including the supraclavicular, thoracic and abdominal regions [6-9]

The short answer is: We do not categorically know yet

Consistent with previous literature, OMMs inducing weight loss also improved blood pressure, with the notable exception of naltrexone plus bupropion, which was associated with an increase in systolic blood pressure 48